Using CD45 as a general marker for leukocytes we found a robust signal for Neo1 within murine whole blood Figure 1C. Taken together these studies suggest that the haematopoetic expression of neogenin significantly promotes an inflammatory response. Figure 7. Matsunaga E, Nakamura H, Chedotal A Repulsive guidance molecule plays multiple roles in neuronal differentiation and axon guidance. Discussion Recent work has demonstrated that the nervous and the immune system share basic biological principles.
View mouse Neo1 Chr with: phenotypes, sequences, ( MPD) · Deltagen and Lexicon Knockout Mice · International Mouse Phenotyping neogenin.
Video: Neogenin knockout mice database Knockout mice
Synonyms. H22Rik, DN22Rik, Igdcc2.
Feature Type. Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse. View mouse Dcc Chr with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.
Video: Neogenin knockout mice database What is MOUSE GENOME INFORMATICS? What does MOUSE GENOME INFORMATICS mean?
Neogenin deficient mice were impaired in digit/limb development and. was also observed in the growth plates of 2–3 weeks old mutant mice (data not shown ).
This implies that neogenin holds an intrinsic role during inflammatory events that is not known to date. Success of transplantation was controlled by identifying switch of hematopoetic Neo1 expression through real time PCR and Western blot analysis.
Nat Cell Biol 6: — In conclusion we identified a previously uncharacterized function for neogenin outside the CNS. Biorbyt antibodies for NEO1.
NEO1 Gene GeneCards NEO1 Protein NEO1 Antibody
Adhesion Angiogenesis Neuroscience.
Netrin-Neogenin interactions result in a chemoattractive axon guidance response and cell-cell adhesion, the interaction between NEO1/Neogenin and RGMa and RGMb induces a chemorepulsive response. as mutations or abnormal levels and includes techniques such as knockouts.
Organism-specific databases. Hide 10 20 30 40 MAAEREAGRL LCTSSSRRCC PPPPLLLLLP LLLLLGRPAS GAAATKSGSP 60 70 80 90 PQSAGASVRT FTPFYFLVEP.
Nature — Family: Belongs to the immunoglobulin superfamily. One of these parallels is the function of neuronal guidance proteins NGP s that were initially described in the context of axonal migration but were demonstrated to also serve as endogenous guidance cues for leukocyte migration.
Discussion Recent work has demonstrated that the nervous and the immune system share basic biological principles. J Intern Med 91—