Relative refractory period physiology of hearing

images relative refractory period physiology of hearing

It should be noted that while Zhang et al. Higher current levels yield faster recovery from refractoriness Finley et al. Materials and methods 2. Please review our privacy policy. Open in a separate window.

  • Response Properties of the Refractory Auditory Nerve Fiber SpringerLink
  • Refractory Periods Neuronal Action Potential PhysiologyWeb

  • Refractoriness is the fundamental property of any object of autowave nature ( especially Absolute refractory period corresponds to depolarization and repolarization, whereas relative refractory period corresponds to hyperpolarization.

    Temporal coding of information is important in the auditory system, where a general mechanism for enhancing spike-time precision in auditory neurons has The absolute refractory period is often estimated in vivo using a stimulus that.

    Response Properties of the Refractory Auditory Nerve Fiber SpringerLink

    Finally, at the most peripheral physiological level, auditory neural There was a trend toward shorter refractory-recovery time constants for.
    Mean data pooled across devices are shown in the top section of Table 4which lists the mean slope of the rate-integration function for electrodes that exhibited maximum alternation in the ECAP pattern at rates ranging from pps to pps no electrodes showed maximum alternation at pps.

    Physiological effects of stimulation rate The electrically evoked compound action potential ECAP is an aggregate response from a collection of auditory-nerve fibers.

    Video: Relative refractory period physiology of hearing Absolute and Relative Refractory Periods

    As stimulation rate increases, thresholds tend to decrease more than upper-comfort levels because the mechanisms that contribute to each measure differ slightly McKay et al. For each rate, the normalized amplitudes for even- and odd-numbered pulses excluding the first pulse were compared using a paired t-test.

    Note: Some functions of this site require your browser to support JavaScript. Correct-answer feedback was provided. One of the benefits of measuring ECAPs in response to each pulse in a train is that we can obtain more detailed information about the temporal processing of sub-populations of neurons, and how the variations in neural responses across pulses within a pulse train relate to its overall percept.

    images relative refractory period physiology of hearing
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    The authors hypothesized that increased neural adaptation would limit the input to the central integrator, thereby reducing the amount of temporal integration.

    Data for each rate are shown from top pps to bottom pps.

    Refractory Periods Neuronal Action Potential PhysiologyWeb

    The spread in the data across the three electrodes i. The group ECAP data average normalized amplitude across pulses were input to a loudness model to predict the rate-integration function.

    Starting level was typically 2.

    The two major auditory structures of the sensorineural mechanism are the cochlea . A neuron can fire during the relative refractory period, but the threshold for. This recovery function vanishes for an absolute refractory period and then .

    trains so that this spiking mechanism reproduces the observed firing rater(t).

    . Similarly, in the auditory system, realistic refractoriness has been. The refractory period of an auditory neuron starts when an action potential has In cochlear implant recipients the relative refractory period of an ECAP lasts up to . This illustrates the general behaviour of the facilitation mechanism, when.
    They also showed that spike-rate adaptation for some fibers can be overcome for slow rates i.

    Membrane charge integration will not occur for very slow rates due to the longer period between pulses exceeding the integrative time window. Results showed a significant negative correlation between the slope of the rate-integration function at T-level and the refractory-recovery time constant, where steeper slopes were obtained for electrodes with slower recovery times.

    images relative refractory period physiology of hearing

    The recording electrode was typically two positions apical to the stimulating electrode; stimulation and recording were both monopolar. PLOS One.

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    images relative refractory period physiology of hearing
    Relative refractory period physiology of hearing
    The neuronal response to electrical constant-amplitude pulse train stimulation: evoked compound action potential recordings.

    In other words, the membrane is made less negative.

    images relative refractory period physiology of hearing

    This period is the relative refractory period. Temporal representations with cochlear implants. Changes across time in the temporal responses of auditory nerve fibers stimulated by electric pulse trains.

    images relative refractory period physiology of hearing

    Autowave Excitable medium Parabolic partial differential equation Reaction-diffusion.

    5 thoughts on “Relative refractory period physiology of hearing”

    1. If the neuron is stimulated with a stimulus strong enough only to bring a resting neuron to threshold, the neuron will only respond when the relative refractory period is over i. J Assoc Res Otolarygol.

    2. ECAP measures required higher stimulus levels than those used for behavioral thresholds because ECAPs were suprathreshold measures obtained with shorter-duration pulse trains, whereas behavioral measures were thresholds obtained with longer-duration pulse trains. Normalized amplitudes do not yield information about the size of the underlying neural population, but rather a percentage of neural activity relative to that of the first pulse in the train.

    3. Views Read Edit View history. In general, psychophysical thresholds and average ECAP amplitudes both decreased as stimulation rate increased.